What about veterinary use? Can LDN help an arthritic dog or a cat with cancer? As Dr. Bahari would say, why not give it a trial. It won’t do any harm and it’ll probably work. We agree and we’ve seen LDN prescriptions for animals, mostly dogs and cats, but there’s no reason to exclude any animal who is suffering from a chronic inflammatory condition.
Smaller animals seem to benefit from smaller doses, 1.5 mg for example. Larger pets might do well using the common human strengths; 3.0 mg and 4.5 mg. While the effective doses seem related to the weight of the “patient” there isn’t yet a specific discussion about which doses work best. As the animal patient gets larger – take horses for example – it may be best to use much higher doses. Regardless of the health situation or the size of the patient, Naltrexone seems a reasonable treatment to try. LDN has the added benefit of increasing endorphins with very little risk of side effects. So, at the very least, it can't hurt to let your pet feel better when they're sick.
For those who are interested, the proper dose of LDN is very small and the formula is this: .03 mg. x weight (This is what has been found most successful from patient trial and error)
In developing Naltrexone for full dose use toxicity testing in rats, rabbits, dogs and monkeys determined that at therapeutic levels Naltrexone was non-toxic and had very few side effects. However obtaining FDA approval for the Low Dose regimen will require funding that due to the present out of patent or generic status of the drug will be difficult to obtain from any pharmaceutical company. Some privately funded pilot studies have been conducted and show much promise. More extensive studies are needed and funding continues to be sought by advocates of LDN.