I do have a cocker spaniel and she is 21.6 lbs. and is on .05 mils LDN every am for her non contagious mange. I will keep her on it for life for her since D…. mange is auto immune. Even though the mites are gone. My last Cocker had live cancer and disease and a bum leg she lived a yr and half long then expected and gained full use of her back leg. My vets was stunned. I was Grateful!