"I had slowly worsening Dupuytren's when I started LDN for other reasons. It stopped getting worse immediately and there was even some improvement. I was doing homeopathic therapies for it at the same time, so I can't say that LDN was the total cure, but it might have been. If it wasn't, then it was an important part of the cure, perhaps the factor that brought success. No sign of it since then; it's been two years now. At the time, someone posted on this listserve that their Dupuytrens "melted away" when they started LDN. Perhaps you can search the archives for more comments about it. I hope it works for you!"